Oxymetholone Profile (Chemical name of Anadrol 50)
- [17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3one]
- Molecular Weight: 332.482
- Molecular Formula: C 21 H 32 O 3
- Melting Point: 178-180C
- Manufacturer: Syntex (Originally)
- Release Date: 1960
- Effective Dose: 100mgs (optimal)
- Active Life: <16hours
- Detection Time: up to 8 weeks
- Anabolic/Androgenic Ratio: 320:45
The effects of Anadrol 50 is without question some of the strongest among anabolic steroids. This is largely considered one of the most powerful steroids in existence, especially on the prescription market, and the results will be rapid. Anadrol is one of the premier mass building steroids, and it will significantly boost the individual’s strength. This steroid is so rapidly powerful it is not uncommon for the individual to gain as much as 20-30lbs in as little as 4-6 weeks of total use. Some of this will undoubtedly be water weight. Anadrol is a non-aromatizing steroid, but it is one of the few non-aromatizing steroids and one of the only DHT compounds that is highly estrogenic. Water retention can be controlled, but this will take some effort in the form of anti-estrogen medications as well as diet.
Due to its fast acting nature, the most common time a performance-enhancing athlete will supplement with Anadrol is at the frontend of a new mass gaining or off-season phase. Often referred to as kick-starting, this will produce rapid gains while the slower injectable steroids are building in your system. This brings us to an important point; Anadrol is not a base steroid but rather a secondary steroid that can be added to a total stack. Those who use Anadrol alone will find rapid gains occur, but they will find they disappear just as fast when the cycle does not continue with base steroids like Testosterone, Nandrolone or Trenbolone.
Another excellent time to use Anadrol is mid-cycle. During any cycle, at some point and time the individual will hit a wall. The gains and progress will slow or even come to a screeching halt. When this occurs something must change. It may be a call for a change in training or diet, or it could be a call to introduce a new yet powerful anabolic agent. Mid-cycle use, often referred to as plateau busting will see the gains continue again. You very well may not gain as much weight as you would with a kick-start, but progress will be made nonetheless. It should be noted; if Anadrol is used as a kick-start it should not be used as a mid-cycle plateau buster. This steroid carries a strong hepatic nature and such double use will provide an enormous amount of stress to the liver.
The final time for a performance enhancing athlete to use Anadrol is during a cutting cycle; however, this will only apply to a select group. Anadrol can be a great steroid for a competitive bodybuilder at the tail end of his contest prep. This will aid him in providing a fuller look on stage as he will be able to fully maximize his carb load. This is without question a more advanced technique and one many people will need to avoid. If you have never used Anadrol before the last thing you want is to use it for contest prep purposes. You need to understand how your body reacts to the hormone, you need to understand how to control water during such a phase of use, and most importantly, you need to be in excellent shape. By excellent shape we’re referring to body fat levels of below 6%. These are levels that most steroid using gym rats will never see. Failure to abide by these rules could easily ruin your contest prep and months of hard work. For those who qualify for this period of supplementation, if conditioned, which is the most important factor, the result will be a physique that appears larger and fuller.
Anadrol 50 is not what we’d call an extremely side effect friendly anabolic steroid. This is largely why its use has become limited in a therapeutic sense. However, the effects can be controlled in most cases. In order to understand the side effects of Anadrol, we have broken them down into their separate categories with all the related information you’ll need.
The Oxymetholone hormone does not aromatize. The aromatase enzyme does not affect it, which is responsible for the conversion of testosterone to estrogen. Further, it is not a progestin and carries no progesterone nature, however, it remains highly estrogenic. How or why it is so estrogenic is a bit of a mystery. There are some theories and the most solid is that Oxymetholone can activate the estrogen receptors to a stronger degree than many other steroids.
Due to the estrogenic nature of Anadrol, gynecomastia can be a real concern, as can excess water retention. In order to protect from gynecomastia you will need an anti-estrogen medication. Anti-estrogens will also have a positive effect on water retention, but when it comes to their use with Anadrol there is an interesting note. The common anti-estrogens used by performance athletes include Selective Estrogen Receptor Modulators (SERM’s) like Tamoxifen Citrate (Nolvadex) and Aromatase Inhibitors (AI’s) like Anastrozole (Arimidex). AI’s are by far the most effective at controlling estrogen as they inhibit aromatization and lower the body’s estrogen levels. SERM’s do not inhibit or lower estrogen but attach to the receptors in the place of estrogen. However, in this case it’s important to remember there is no aromatization going on, there is nothing for an AI to inhibit. They will still be the most effective means of protection due to their reducing properties, but some will find SERM’s to be enough. As an added bonus, SERM’s will not negatively affect cholesterol, while AI’s most certainly will.
A final note, controlling excess water retention is very important. If excess water retention gets out of hand it can have a negative impact on blood pressure.
Anadrol carries with it some strong androgenic related side effects despite its rather low androgenicity. The androgenic side effects of Anadrol can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. These are, however, very genetically based side effects. For example, many who supplement will not have a problem with acne, but those who are genetically sensitive may find they have a problem. It should also be noted; 5-alpha reductase inhibitors will not affect this steroids androgenicity. It is the 5-alpha reductase enzyme that causes testosterone to reduce to DHT, but in this case there is nothing to inhibit as Oxymetholone is already a DHT compound.
The androgenic nature of Anadrol causes this steroid to be a poor choice for women. The use of Oxymetholone will lead to severe virilization symptoms such as body hair growth, a deepening of the vocal chords and clitoral enlargement. Many often find it to also have a reducing effect on breast size and to promote menstrual irregularity. While women can safely supplement with some anabolic steroids, this is not one of them. Women should choose steroids with a weakened androgenic nature.
The Oxymetholone hormone can have a strong negative impact on cholesterol, particularly HDL levels. While it does not appear to have a significant impact on LDL levels it will greatly suppress HDL cholesterol. It is imperative that those who suffer from high cholesterol do not supplement with this anabolic steroid. In fact, anabolic steroids in general should be avoided if the individual does not possess a healthy cholesterol reading. For those who are healthy enough for supplementation it will be extremely important that they live a lifestyle that is conducive to maintaining proper levels. The individual’s diet will be the most important factor. Large amounts of saturated fats should be avoided, as well as generally unfriendly cholesterol foods. The supplementation of omega fatty acids is also highly recommended, as is plenty of cardiovascular activity.
The use of anabolic steroids will suppress natural testosterone. The rate of suppression is dependent on the steroid in question, but in the case of Oxymetholone it is enough to warrant the use of exogenous testosterone. This will actually hold true with most anabolic steroids. Those who supplement with Anadrol and forgo exogenous testosterone therapy will fall into a low testosterone condition. Not only is this a condition that comes with numerous bothersome symptoms, it is an extremely unhealthy state. The form of testosterone you choose when using Anadrol is of no consequence, however, you should ensure you are applying enough to provide what the body needs.
Once the use of Anadrol and all anabolic steroids has come to an end and all the exogenous hormones have cleared your system natural testosterone production will begin again. This is assuming there was no prior existing low level state. It also assumes no damage was done to the HPTA during supplementation due to improper practices. While natural testosterone production will begin again on its own, it will not be fast. It is generally recommended that the individual begin a Post Cycle Therapy (PCT) treatment plan following anabolic steroid use. This will encourage natural testosterone production and speed the healing process up. It will not automatically return you to your previous natural high level on its own; that will take some time. However, it will ensure you have enough testosterone in your body to function properly while your levels continue to naturally rise.
Oxandrolone is most certainly a hepatotoxic steroid. It does not carry the strongest level of hepatotoxicity among anabolic steroids, but it is stronger than most. This is due to it being a C17-aa anabolic steroid. All C17-aa steroids are hepatic, but the level of toxicity varies greatly between them. Due to this steroid’s strong hepatotoxicity, this is why total use must be limited (see administration section).
Due to use, those who supplement with Anadrol will find their liver enzyme values increase. An increase in values is not a sign of damage but rather a sign of stress that can lead to damage if responsible practices are not followed and the stress is allowed to remain. Proper dosing and duration of use protocols are imperative when it comes to this steroid. Further, it is important the individual avoids excess alcohol consumption when supplementing with this steroid due to the liver stress such consumption will cause. In fact, most will find avoiding all alcohol to be best during use. If this is a problem and you are supplementing for the purpose of performance enhancement remember there is nothing on earth that is as anti-performance as alcohol. Those who supplement are also encouraged to limit their use of Over the Counter (OTC) medications. Many OTC medications carry strong hepatic natures, and the added stress can be extensive when coupled with Anadrol. Use should be limited to when only absolutely needed. If these rules can be followed, once use is discontinued liver enzyme values will return to normal and no damage will be done. As a final note, Anadrol should not be used if the liver is unhealthy.